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In some emboduments, the administering the composition reduces the patient’s fractional exhaled nitric oxide (FeNO) by at least 20% after 1 month of administration (e.g., twice daily) of the composition

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The endoplasmic reticulum is highly sensitive to oxidative stress, and ROS can induce its stress state, leading to melanocyte apoptosis (Xie et al., 2024)